This weekend, there are numerous games and… These are the Best:
| – | Team | Rank | VS | Rank | Opp Team | Details |
| 1 | Florida | #8 | vs | #14 | Temple | 05/08/2021 |
| 2 | Drexel | #7 | vs | #27 | Towson | 05/07/2021 |
| 3 | Loyola | #12 | vs | #25 | Lehigh | 05/08/2021 |
| 4 | Stanford | #9 | vs | #28 | Colorado | 05/08/2021 |
| 5 | James Madison | #20 | vs | #18 | Hofstra | 05/07/2021 |
| 6 | Stony Brook | #10 | vs | #30 | UAlbany | 05/08/2021 |
| 7 | Denver | #16 | vs | #32 | UConn | 05/08/2021 |
| 8 | Jacksonville | #17 | vs | #45 | Liberty | 05/08/2021 |
| 9 | Mount St Mary’s | #33 | vs | #74 | Wagner | 05/08/2021 |
| 10 | Fairfield | #46 | vs | #63 | Siena | 05/09/2021 |
| 11 | Furman | #52 | vs | #65 | Mercer | 05/08/2021 |
| 12 | Robert Morris | #39 | vs | #111 | Detroit Mercy | 05/08/2021 |
| 13 | Central Michigan | #54 | vs | #108 | Youngstown State | 05/08/2021 |
| 14 | Akron | #101 | vs | #96 | Kent State | 05/08/2021 |
