All teams are ranked according to their Best Wins and Worst Losses in 2021. In other words, if an objectively pretty good team only has 2 wins, they will have a lower rank than they objectively should have.
| – | Team | Rank | VS | Rank | Opp Team | Details |
| 1 | North Carolina | #1 | vs | #6 | Virginia | 04/18/2021 |
| 2 | Boston College | #3 | vs | #4 | Notre Dame | 04/17/2021 |
| 3 | North Carolina | #1 | vs | #6 | Virginia | 04/16/2021 |
| 4 | Northwestern | #5 | vs | #18 | Michigan | 04/18/2021 |
| 5 | Maryland | #12 | vs | #15 | Johns Hopkins | 04/16/2021 |
| 6 | Florida | #8 | vs | #22 | Vanderbilt | 04/18/2021 |
| 7 | Florida | #8 | vs | #22 | Vanderbilt | 04/16/2021 |
| 8 | Penn State | #16 | vs | #15 | Johns Hopkins | 04/18/2021 |
| 9 | Louisville | #30 | vs | #2 | Syracuse | 04/18/2021 |
| 10 | Louisville | #30 | vs | #2 | Syracuse | 04/16/2021 |
| 11 | Rutgers | #21 | vs | #12 | Maryland | 04/18/2021 |
| 12 | Drexel | #9 | vs | #25 | Hofstra | 04/18/2021 |
| 13 | Rutgers | #21 | vs | #16 | Penn State | 04/16/2021 |
| 14 | Michigan | #18 | vs | #24 | Ohio State | 04/16/2021 |
| 15 | Arizona State | #34 | vs | #17 | Stanford | 04/16/2021 |
| 16 | James Madison | #33 | vs | #23 | Towson | 04/18/2021 |
| 17 | USC | #44 | vs | #17 | Stanford | 04/18/2021 |
| 18 | Duke | #7 | vs | #54 | Virginia Tech | 04/17/2021 |
| 19 | Marquette | #48 | vs | #14 | Denver | 04/18/2021 |
| 20 | Marquette | #48 | vs | #14 | Denver | 04/16/2021 |
| 21 | Furman | #56 | vs | #10 | Jacksonville | 04/16/2021 |
| 22 | Loyola | #13 | vs | #57 | Bucknell | 04/17/2021 |
| 23 | Villanova | #50 | vs | #31 | UConn | 04/18/2021 |
| 24 | Villanova | #50 | vs | #31 | UConn | 04/16/2021 |
| 25 | Davidson | #28 | vs | #59 | George Washington | 04/16/2021 |
