In order, these are today’s Best Games.
| – | Team | Rank | VS | Rank | Opp Team | Details |
| 1 | Washington and Lee | #10 | vs | #4 | Christopher Newport | 04/20/2021 |
| 2 | York | #7 | vs | #73 | Hood | Postponed |
| 3 | Lasell | #66 | vs | #76 | Norwich | 04/20/2021 |
| 4 | Wooster | #134 | vs | #22 | Ohio Wesleyan | 04/20/2021 |
| 5 | Eastern Connecticut | #113 | vs | #80 | UMass-Boston | 04/20/2021 |
| 6 | DePauw | #161 | vs | #55 | Denison | 04/20/2021 |
| 7 | Albion | #59 | vs | #177 | Adrian | 04/20/2021 |
| 8 | Castleton | #211 | vs | #43 | Keene State | 04/20/2021 |
| 9 | Trine | #159 | vs | #97 | Calvin | 04/20/2021 |
| 10 | Illinois Tech | #178 | vs | #81 | Benedictine | 04/20/2021 |
| 11 | Hope | #62 | vs | #201 | Kalamazoo | 04/20/2021 |
| 12 | Saint Joseph’s (ME) | #111 | vs | #154 | Rivier | 04/20/2021 |
| 13 | Bryn Athyn | #123 | vs | #145 | Rosemont | 04/20/2021 |
| 14 | Kean | #77 | vs | #205 | Keystone | 04/20/2021 |
| 15 | St. Joseph (CT) | #170 | vs | #122 | Dean | 04/20/2021 |
| 16 | Centenary (NJ) | #208 | vs | #90 | Montclair State | 04/20/2021 |
| 17 | Aurora | #102 | vs | #217 | Concordia-Chicago | 04/20/2021 |
| 18 | Concordia-Wisconsin | #175 | vs | #155 | Marian | 04/20/2021 |
| 19 | Southern Maine | #189 | vs | #158 | Plymouth State | 04/20/2021 |
| 20 | Edgewood | #224 | vs | #148 | MSOE | 04/20/2021 |
| 21 | LaGrange | #190 | vs | #218 | Brevard | 04/20/2021 |
