All teams are ranked according to their Best Wins and Worst Losses in 2021. In other words, if an objectively pretty good team, like Johns Hopkins or Notre Dame only has 2 wins, they will have a lower rank than they objectively should have.
| – | Team | Rank | VS | Rank | Opp Team | Details |
| 1 | Syracuse | #6 | vs | #3 | North Carolina | 04/17/2021 |
| 2 | Maryland | #2 | vs | #18 | Ohio State | 04/18/2021 |
| 3 | Georgetown | #11 | vs | #10 | Denver | 04/17/2021 |
| 4 | UMass | #15 | vs | #12 | Towson | 04/17/2021 |
| 5 | Loyola | #16 | vs | #19 | Navy | 04/17/2021 |
| 6 | Vermont | #27 | vs | #14 | UAlbany | Postponed |
| 7 | Army | #8 | vs | #35 | Boston University | 04/17/2021 |
| 8 | Johns Hopkins | #36 | vs | #7 | Rutgers | 04/17/2021 |
| 9 | Hofstra | #26 | vs | #22 | Delaware | 04/17/2021 |
| 10 | Virginia | #4 | vs | #44 | Utah | 04/17/2021 |
| 11 | Richmond | #17 | vs | #34 | Jacksonville | 04/17/2021 |
| 12 | Bryant | #25 | vs | #31 | Saint Joseph’s | 04/17/2021 |
| 13 | Michigan | #32 | vs | #29 | Penn State | 04/16/2021 |
| 14 | Fairfield | #51 | vs | #13 | Drexel | 04/17/2021 |
| 15 | Stony Brook | #20 | vs | #45 | Binghamton | 04/16/2021 |
| 16 | Lehigh | #5 | vs | #61 | Lafayette | 04/18/2021 |
| 17 | Lafayette | #61 | vs | #5 | Lehigh | 04/16/2021 |
| 18 | High Point | #28 | vs | #40 | Mercer | 04/17/2021 |
| 19 | Providence | #30 | vs | #38 | Marquette | 04/17/2021 |
| 20 | Bucknell | #49 | vs | #24 | Robert Morris | 04/16/2021 |
| 21 | St. John’s | #53 | vs | #21 | Villanova | 04/17/2021 |
| 22 | UMBC | #23 | vs | #60 | UMass Lowell | 04/17/2021 |
| 23 | Holy Cross | #47 | vs | #39 | Colgate | 04/17/2021 |
| 24 | Detroit Mercy | #55 | vs | #33 | Marist | 04/17/2021 |
| 25 | LIU | #42 | vs | #46 | Mount St Mary’s | 04/17/2021 |
