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Re: All things CoronaVirus

Posted: Fri Aug 27, 2021 9:31 am
by Bart
wgdsr wrote: Fri Aug 27, 2021 8:48 am
Bart wrote: Fri Aug 27, 2021 8:06 am
tech37 wrote: Fri Aug 27, 2021 7:56 am
Bart wrote: Fri Aug 27, 2021 7:54 am Perhaps this has been put out there, perhaps not but this is a July 28 meta on Ivermectin. Read and conclude what you want.

https://www.cochranelibrary.com/cdsr/do ... .pub2/full

Still waiting on the results of the PRINCIPAL trial. Hopefully those will be out soon-ish'
Which "PRINCIPAL" trial are you referring to?
I just edited the original post for an incorrect spelling of the trial....my bad.(8/27, 8:07)

https://www.principletrial.org/news/ive ... iple-trial

I have been unable to find either results or cancellation of the trial. I am assuming they are waiting on data? IDK. Seems like a good RCT to me.

In a different vein, here is a review of mRNA vaccines from Nature Reviews: Drug Discovery. Whether you agree or not with the platform it is a very interesting read.

https://www.nature.com/articles/s41573-021-00283-5
thanks bart. reading thru principle, they note inhaled budesonide as a potentially effective therapeutic, and that uk, canada and india are using.

one small study of budesonide:
https://www.thelancet.com/article/S2213 ... 0/fulltext

couple things: have not heard of this, at all.
i had read last year in several spots that nebulizing drugs so they can much more efficiently get into lungs and blood could be a real game changer.
for more effectively fighting where covid gets bad, and for utilizing much smaller dosages for drugs that are only effective in the petri dish at higher levels. i've been waiting to see if there was ever going to be a nebulizer boom.

also... why are these "early" trials always using 7 and sometimes14 days as a cutoff for early? seems like maybe 4 -5 days might be a better idea... symptom, test, result, come in within 2 days.

anyway, corticosteroids again.
I agree, that this is rather puzzleing? I am thinking that this is exactly where the "break through" therapeutic may originate.

There are many, many drugs administered in this manner so why not a therapeutic for COVID? I can envision a drug using a nonsense nucleotide analog (Remdesivir) encapsulated in some type of lipid nanoparticle administered via nebulization. The analogs are more stable than the mRNA in the vaccine so why not attempt this? I can only imagine there are smarter people than me working on this as I type.

Re: All things CoronaVirus

Posted: Fri Aug 27, 2021 10:01 am
by wgdsr
jhu72 wrote: Fri Aug 27, 2021 9:12 am Americas Frontline Doctors scam.
don't ever underestimate the pursuit of the american dream. and in a lot of these folks' cases, stupidity.
no idea if ivermectin works. but i wouldn't be waiting around for a call back a week or longer later even if i did!

Re: All things CoronaVirus

Posted: Fri Aug 27, 2021 10:14 am
by MDlaxfan76
tech37 wrote: Fri Aug 27, 2021 7:33 am
MDlaxfan76 wrote: Fri Aug 27, 2021 7:23 am There's no magical exception for a doctor stupidly prescribing a drug off-label for something he explicitly knows is not an authorized or approved usage, indeed has been warned not to prescribe for this purpose.
"stupidly"?...think you're offering an "out of school" opinion once again.

Now, the question of damages is another thing...but if patients took the drug on this advice and either were harmed directly by the drug or were told that they now had immunity and thus did not need to take other protective measures to avoid infection and then were infected, liability indeed would be on the doctor who made that off-label prescription.
If the physician/inmates followed proper protocols, there won't be any harm caused, based upon decades of safe IVM usage in humans.

But yeah, the doctor should lose his license, pay any liability penalty found, and the county folks may well be liable in other ways.

That said, if no one ended up being poisoned or otherwise harmed, there's not really liability.
Seems correct.
No, I mean exactly that: stupidly.
The doctors have been explicitly and expressly warned not to prescribe or otherwise encourage the off-label usage of ivermectin in Covid cases. And, thus, doing so opens them up directly to liability.

Now, again, if the doc is lucky, there won't be any actual or at least not severe damage done and so the damage costs would be minimal...but a class action suit is really, really expensive to defend and the State is likely to have to pony up something to settle, should that occur (meaning the plaintiffs and their counsel have a real incentive to force the issue)...the doctor may be able to just call his malpractice insurance company and say 'oops', but he's quite likely to lose his license and/or face much, much higher malpractice insurance costs going forward if allowed to continue. So...stupidly.

Re: All things CoronaVirus

Posted: Fri Aug 27, 2021 11:38 am
by MDlaxfan76
CU88 wrote: Fri Aug 27, 2021 8:54 am Get your masks for winter. Kids need the right size.

https://yourlocalepidemiologist.substac ... ource=copy

Here is some of the text, link above has graphics and hyperlinks.

Schools: Mitigation measures in the light of Delta

Katelyn Jetelina

We know that mitigation measures like masks, ventilation, and distancing worked very well in schools last year. Study after study after study after study after study showed this. But this was pre-Delta. Do the same mitigation measures still work in schools? This is what we know so far…

Transmission

In the beginning of the pandemic, we were most concerned about droplets of transmission. But we learned quickly (or not so quickly) that aerosol transmission is mainly driving this disease. In July 2020, 239 scientists wrote a letter to the World Health Organization indicating their concern about aerosol transmission. In April 2021, the WHO changed their guidance and, in May 2021, the CDC changed its guidance that recognized airborne spread as a key mode of infection.

The difference between droplets and aerosol are the size and, thus, the implications of that size. Droplets are large (50-100 micrometers) and so they are heavier. Droplets can travel up to 6 feet, but then they fall to the ground due to gravity. This is why the famous 6 foot rule was implemented. People spread droplets by coughing and sneezing.

Aerosols, on the other hand, are much tinier (<5 micrometers) and lightweight, so they can become suspended in air and float. And you don’t need to sneeze or cough. These can be spread by just talking. Lab studies have shown that aerosols can stay in the air for up to 16 hours. So, a sick person doesn’t need to be in the room with you. They could be in the room before you and had left particles everywhere.

Surface (i.e. fomite) transmission is just not as common, but it can happen. Mathematical models estimated that each contact with a contaminated surface has a 1 in 10,000 chance of infection. In a recent study with hamsters, we saw that surface transmission can result in virus in the nose. But, importantly, the virus does not land directly into the lungs like aerosols do. So the virus replicates less, usually leading to less disease severity.


Leung, N.H.L. Transmissibility and transmission of respiratory viruses. Nat Rev Microbiol19, 528–545 (2021). https://doi.org/10.1038/s41579-021-00535-6
Delta is incredibly transmissible with a higher viral load. This changes how easy it enters our cells once it reaches us. It seems to becoming more aerosolized too. While washing hands is always a good idea and 3-6 foot distance helps with droplet transmission, we need effective measures to reduce aerosol transmission in schools.

Ventilation

This continues to be one of the best ways to curb transmission. An open window can do a lot to reduce transmission in the classroom from an infected student. The NYT did a great job visualizing the impact of a window in a classroom.


A study this week found that open windows in classrooms can have up to a 14.1 fold reduction in COVID19 transmission. This is highly dependent on the time of year (Summer, Spring, Winter), number of windows, and the frequency in which those windows are open. For example, an open window during the winter is much more impactful than an open window during the summer (14.1 fold decrease vs. 7.2 fold decrease). Also, just opening the window during recess can help a little but not as good as opening a window all day long.


A fan and clean air filter works great too. This can be accomplished using high-efficiency particulate air (HEPA) filtration systems. A Johns Hopkins study found that HEPA filters were responsible for a 65% drop in COVID-19 transmission. Another study found that one HEPA filter is as effective as two windows partly open all day during the winter (2.5-fold decrease in transmission). Two HEPA filters are even more effective (4-fold decrease in transmission).


Masks

Pre-Delta, we knew masks worked very well. Loose fitting masks, like double cloth masks, even still blocked 51% of particles. With Delta, though, we really need to start wearing better masks, especially those that are most vulnerable (i.e. unvaccinated). A Finland study found that Delta was transmitted among healthcare workers using surgical masks; it’s clear that N95’s work best in hospital settings where employees are constantly exposed to COVID-19.

A stimulation study that came out this week showed that, in classrooms, surgical masks reduce transmission 8-fold. Surgical masks have a great filter, but sometimes they are way too loose on kids. Fit and filter are very important with Delta. For great masks look for ASTM-certified surgical or tight-fitting cloth masks for kids. For fantastic masks, look for KN95 or KF94 made for kids. N95’s are not made for kids, so do not buy them for kids to wear; they don’t fit correctly. Dr. Eva Enns from the University of Minnesota School of Public Health put together an amazing list with specific kid mask brands here. Dr. Linsey Marr at Virigina Tech also made an amazing list here.

Outdoor transmission

There is no shortage of anecdotal evidence of outdoor transmission with Delta, especially in shoulder-to-shoulder activities like festivals. In Melbourne, two playgrounds and one skate park were exposure sites, which has fueled a stark debate about shutdowns in Australia. Importantly, these events seem to be largely crowded. Any time you’re close enough to breathe in air from someone else’s breath you have a chance of being infected. Being outdoors continues to be much less risky than indoors. Indoors can accumulate aerosols a whole lot more than outdoors. Think about it like smoking cigarettes. If someone is smoking cigarettes indoors, there is far more buildup over time than someone smoking outdoors.

Testing

With Delta, cases are going to happen in schools. Even if mitigation measures are in place. This virus is far too transmissible and contagious to not expect this. So, we need to identify cases proactively to stop the possibility of superspreader events. Schools need plans in place for testing, contact tracing, quarantining, and reporting. This includes supporting kids that are in quarantine through distanced learning. Your local health department will not have the bandwidth to do this, especially if you’re in a hotspot. There are great playbooks out there, though, to help guide testing strategies. Some states, like Texas, actually have frameworks. Rockefeller had a great playbook on this too.


Layered approach

The one thing that is incredibly clear is that we need a layered approach for Delta. Combined interventions (i.e., natural ventilation, masks, and HEPA filtration) are the most effective in schools (≥30-fold decrease in transmission). The more layers we have, the less chance virus gets through the Swiss cheese to your kid. This is an ever evolving landscape and we need to adapt and advocate accordingly.

Love, YLE
Finally, a really clear set of guidelines and explanations thereof.

Re: All things CoronaVirus

Posted: Fri Aug 27, 2021 11:51 am
by PizzaSnake
jhu72 wrote: Fri Aug 27, 2021 9:12 am Americas Frontline Doctors scam.
Fear makes grifting easier. Which circle would Dante assign them to? And which circle for the "mis-informationistas"?

Tarring and feathering might be a good start... I nominate Abbot and DeSatan for the first recipients.

Re: All things CoronaVirus

Posted: Fri Aug 27, 2021 1:52 pm
by tech37
wgdsr wrote: Fri Aug 27, 2021 10:01 am
jhu72 wrote: Fri Aug 27, 2021 9:12 am Americas Frontline Doctors scam.
don't ever underestimate the pursuit of the american dream. and in a lot of these folks' cases, stupidity.
no idea if ivermectin works. but i wouldn't be waiting around for a call back a week or longer later even if i did!
Right. Show us one line of business where scams haven't been tried. Caveat emptor!

Re: All things CoronaVirus

Posted: Fri Aug 27, 2021 2:29 pm
by Farfromgeneva
Kid in my sons class just got the HIV, or I mean Covid. They just sent emails out. They’re not quarantining yet so they’re sticking with in school for now. Will be interesting to see how this shakes out.

Re: All things CoronaVirus

Posted: Fri Aug 27, 2021 4:14 pm
by jhu72
PizzaSnake wrote: Fri Aug 27, 2021 11:51 am
jhu72 wrote: Fri Aug 27, 2021 9:12 am Americas Frontline Doctors scam.
Fear makes grifting easier. Which circle would Dante assign them to? And which circle for the "mis-informationistas"?

Tarring and feathering might be a good start... I nominate Abbot and DeSatan for the first recipients.
... I think this speaks to the people who are customers of these clowns as well. They pay $90 for the script and who knows how much for the meds of questionable value, if they can get it; rather than pay $0 for the vaccine that is known to work. Is this smart?? This is more than mis-information, this takes a beyond all reason stiff neck in many.

Re: All things CoronaVirus

Posted: Fri Aug 27, 2021 5:45 pm
by Typical Lax Dad

Re: All things CoronaVirus

Posted: Fri Aug 27, 2021 5:53 pm
by jhu72
Yet another dumbass, with young children, no mask, no vaccination, soon to be dead. Probably couldn't get Ivermectin or Hydroxychloroquine. Should have gone with the Clorox. At least he has his freedom. :roll: I guess his wife and kids do too.

Re: All things CoronaVirus

Posted: Fri Aug 27, 2021 6:01 pm
by tech37
jhu72 wrote: Fri Aug 27, 2021 4:14 pm
PizzaSnake wrote: Fri Aug 27, 2021 11:51 am
jhu72 wrote: Fri Aug 27, 2021 9:12 am Americas Frontline Doctors scam.
Fear makes grifting easier. Which circle would Dante assign them to? And which circle for the "mis-informationistas"?

Tarring and feathering might be a good start... I nominate Abbot and DeSatan for the first recipients.
... I think this speaks to the people who are customers of these clowns as well. They pay $90 for the script and who knows how much for the meds of questionable value, if they can get it; rather than pay $0 for the vaccine that is known to work. Is this smart?? This is more than mis-information, this takes a beyond all reason stiff neck in many.
jhu72... to your knowledge, has your Dr. wife ever prescribed any medication off-label?... just curious

If so, I would bet that is a freedom and private transaction between herself and her patients she wouldn't want to lose.

Unfortunately, the IVM/Covid construct has become completely politicized by a concerted effort, (the health establishment and others), to link it to HCQ, anti-vaxxers, and Trump. All lies/misinformation. You know this of course but would never pass up a chance to throw partisan bricks.

At this point, no one stands a chance of acquiring a script of IVM, for either prophylactic or treatment protocols against Covid, in the privacy of their doctor's office. Mission accomplished I guess.

Re: All things CoronaVirus

Posted: Fri Aug 27, 2021 6:06 pm
by Typical Lax Dad
tech37 wrote: Fri Aug 27, 2021 6:01 pm
jhu72 wrote: Fri Aug 27, 2021 4:14 pm
PizzaSnake wrote: Fri Aug 27, 2021 11:51 am
jhu72 wrote: Fri Aug 27, 2021 9:12 am Americas Frontline Doctors scam.
Fear makes grifting easier. Which circle would Dante assign them to? And which circle for the "mis-informationistas"?

Tarring and feathering might be a good start... I nominate Abbot and DeSatan for the first recipients.
... I think this speaks to the people who are customers of these clowns as well. They pay $90 for the script and who knows how much for the meds of questionable value, if they can get it; rather than pay $0 for the vaccine that is known to work. Is this smart?? This is more than mis-information, this takes a beyond all reason stiff neck in many.
jhu72... to your knowledge, has your Dr. wife ever prescribed any medication off-label?... just curious

If so, I would bet that is a freedom and private transaction between herself and her patients she wouldn't want to lose.

Unfortunately, the IVM/Covid construct has become completely politicized by a concerted effort, (the health establishment and others), to link it to HCQ, anti-vaxxers, and Trump. All lies/misinformation. You know this of course but would never pass up a chance to throw partisan bricks.

At this point, no one stands a chance of acquiring a script of IVM, for either prophylactic or treatment protocols against Covid, in the privacy of their doctor's office. Mission accomplished I guess.
https://www.fda.gov/patients/learn-abou ... rugs-label

Re: All things CoronaVirus

Posted: Fri Aug 27, 2021 6:53 pm
by jhu72
tech37 wrote: Fri Aug 27, 2021 6:01 pm
jhu72 wrote: Fri Aug 27, 2021 4:14 pm
PizzaSnake wrote: Fri Aug 27, 2021 11:51 am
jhu72 wrote: Fri Aug 27, 2021 9:12 am Americas Frontline Doctors scam.
Fear makes grifting easier. Which circle would Dante assign them to? And which circle for the "mis-informationistas"?

Tarring and feathering might be a good start... I nominate Abbot and DeSatan for the first recipients.
... I think this speaks to the people who are customers of these clowns as well. They pay $90 for the script and who knows how much for the meds of questionable value, if they can get it; rather than pay $0 for the vaccine that is known to work. Is this smart?? This is more than mis-information, this takes a beyond all reason stiff neck in many.
jhu72... to your knowledge, has your Dr. wife ever prescribed any medication off-label?... just curious

If so, I would bet that is a freedom and private transaction between herself and her patients she wouldn't want to lose.

Unfortunately, the IVM/Covid construct has become completely politicized by a concerted effort, (the health establishment and others), to link it to HCQ, anti-vaxxers, and Trump. All lies/misinformation. You know this of course but would never pass up a chance to throw partisan bricks. -- I largely reject this conspiracy theory.

At this point, no one stands a chance of acquiring a script of IVM, for either prophylactic or treatment protocols against Covid, in the privacy of their doctor's office. Mission accomplished I guess.
... off label use, I don't know, but would doubt it. Don't hear her talking about circumstances where that would be useful. She does prescribe/recommend vitamins, but those aren't drugs controlled by the FDA, they are considered dietary supplements.

Re: All things CoronaVirus

Posted: Fri Aug 27, 2021 7:03 pm
by jhu72
Typical Lax Dad wrote: Fri Aug 27, 2021 6:06 pm
tech37 wrote: Fri Aug 27, 2021 6:01 pm
jhu72 wrote: Fri Aug 27, 2021 4:14 pm
PizzaSnake wrote: Fri Aug 27, 2021 11:51 am
jhu72 wrote: Fri Aug 27, 2021 9:12 am Americas Frontline Doctors scam.
Fear makes grifting easier. Which circle would Dante assign them to? And which circle for the "mis-informationistas"?

Tarring and feathering might be a good start... I nominate Abbot and DeSatan for the first recipients.
... I think this speaks to the people who are customers of these clowns as well. They pay $90 for the script and who knows how much for the meds of questionable value, if they can get it; rather than pay $0 for the vaccine that is known to work. Is this smart?? This is more than mis-information, this takes a beyond all reason stiff neck in many.
jhu72... to your knowledge, has your Dr. wife ever prescribed any medication off-label?... just curious

If so, I would bet that is a freedom and private transaction between herself and her patients she wouldn't want to lose.

Unfortunately, the IVM/Covid construct has become completely politicized by a concerted effort, (the health establishment and others), to link it to HCQ, anti-vaxxers, and Trump. All lies/misinformation. You know this of course but would never pass up a chance to throw partisan bricks.

At this point, no one stands a chance of acquiring a script of IVM, for either prophylactic or treatment protocols against Covid, in the privacy of their doctor's office. Mission accomplished I guess.
https://www.fda.gov/patients/learn-abou ... rugs-label
... doctors put themselves at risk by prescribing for off-label use. If there is an adverse reaction, or the patient doesn't progress where they would have with some on-label drug, its a lawyers wet dream. Most (not all) off-label use is through approved clinical trials, which if things go well can lead to a label change for the drug.

Re: All things CoronaVirus

Posted: Fri Aug 27, 2021 7:15 pm
by Typical Lax Dad

Re: All things CoronaVirus

Posted: Fri Aug 27, 2021 7:48 pm
by tech37
jhu72 wrote: Fri Aug 27, 2021 6:53 pm
tech37 wrote: Fri Aug 27, 2021 6:01 pm
jhu72 wrote: Fri Aug 27, 2021 4:14 pm
PizzaSnake wrote: Fri Aug 27, 2021 11:51 am
jhu72 wrote: Fri Aug 27, 2021 9:12 am Americas Frontline Doctors scam.
Fear makes grifting easier. Which circle would Dante assign them to? And which circle for the "mis-informationistas"?

Tarring and feathering might be a good start... I nominate Abbot and DeSatan for the first recipients.
... I think this speaks to the people who are customers of these clowns as well. They pay $90 for the script and who knows how much for the meds of questionable value, if they can get it; rather than pay $0 for the vaccine that is known to work. Is this smart?? This is more than mis-information, this takes a beyond all reason stiff neck in many.
jhu72... to your knowledge, has your Dr. wife ever prescribed any medication off-label?... just curious

If so, I would bet that is a freedom and private transaction between herself and her patients she wouldn't want to lose.

Unfortunately, the IVM/Covid construct has become completely politicized by a concerted effort, (the health establishment and others), to link it to HCQ, anti-vaxxers, and Trump. All lies/misinformation. You know this of course but would never pass up a chance to throw partisan bricks. -- I largely reject this conspiracy theory.

At this point, no one stands a chance of acquiring a script of IVM, for either prophylactic or treatment protocols against Covid, in the privacy of their doctor's office. Mission accomplished I guess.
... off label use, I don't know, but would doubt it. Don't hear her talking about circumstances where that would be useful. She does prescribe/recommend vitamins, but those aren't drugs controlled by the FDA, they are considered dietary supplements.
Re your "conspiracy" claim...

When there is conclusive evidence that IVM off-label use is causing harm or deaths (according to all the trendy admonishments), I'll change my mind. Until then, this continuing concerted effort by the health establishment and Big Pharma, now captured by partisan political actors to discredit the drug and anyone who proposes it's off-label use, cancels a tool (that could keep people out of the ICU) for doctors and patients to battle Covid. Let's see how long it takes Big Pharma (Merck) to come up with an at-home therapeutic and then how much longer before they're allowed to release it. Don't hold your breath.

Re: All things CoronaVirus

Posted: Fri Aug 27, 2021 7:59 pm
by Typical Lax Dad
tech37 wrote: Fri Aug 27, 2021 7:48 pm
jhu72 wrote: Fri Aug 27, 2021 6:53 pm
tech37 wrote: Fri Aug 27, 2021 6:01 pm
jhu72 wrote: Fri Aug 27, 2021 4:14 pm
PizzaSnake wrote: Fri Aug 27, 2021 11:51 am
jhu72 wrote: Fri Aug 27, 2021 9:12 am Americas Frontline Doctors scam.
Fear makes grifting easier. Which circle would Dante assign them to? And which circle for the "mis-informationistas"?

Tarring and feathering might be a good start... I nominate Abbot and DeSatan for the first recipients.
... I think this speaks to the people who are customers of these clowns as well. They pay $90 for the script and who knows how much for the meds of questionable value, if they can get it; rather than pay $0 for the vaccine that is known to work. Is this smart?? This is more than mis-information, this takes a beyond all reason stiff neck in many.
jhu72... to your knowledge, has your Dr. wife ever prescribed any medication off-label?... just curious

If so, I would bet that is a freedom and private transaction between herself and her patients she wouldn't want to lose.

Unfortunately, the IVM/Covid construct has become completely politicized by a concerted effort, (the health establishment and others), to link it to HCQ, anti-vaxxers, and Trump. All lies/misinformation. You know this of course but would never pass up a chance to throw partisan bricks. -- I largely reject this conspiracy theory.

At this point, no one stands a chance of acquiring a script of IVM, for either prophylactic or treatment protocols against Covid, in the privacy of their doctor's office. Mission accomplished I guess.
... off label use, I don't know, but would doubt it. Don't hear her talking about circumstances where that would be useful. She does prescribe/recommend vitamins, but those aren't drugs controlled by the FDA, they are considered dietary supplements.
Re your "conspiracy" claim...

When there is conclusive evidence that IVM off-label use is causing harm or deaths (according to all the trendy admonishments), I'll change my mind. Until then, this continuing concerted effort by the health establishment and Big Pharma, now captured by partisan political actors to discredit the drug and anyone who proposes it's off-label use, cancels a tool (that could keep people out of the ICU) for doctors and patients to battle Covid. Let's see how long it takes Big Pharma (Merck) to come up with an at-home therapeutic and then how much longer before they're allowed to release it. Don't hold your breath.
What do you think of root tonic as a treatment for COVID-19?

Re: All things CoronaVirus

Posted: Fri Aug 27, 2021 9:46 pm
by Farfromgeneva
jhu72 wrote: Fri Aug 27, 2021 7:03 pm
Typical Lax Dad wrote: Fri Aug 27, 2021 6:06 pm
tech37 wrote: Fri Aug 27, 2021 6:01 pm
jhu72 wrote: Fri Aug 27, 2021 4:14 pm
PizzaSnake wrote: Fri Aug 27, 2021 11:51 am
jhu72 wrote: Fri Aug 27, 2021 9:12 am Americas Frontline Doctors scam.
Fear makes grifting easier. Which circle would Dante assign them to? And which circle for the "mis-informationistas"?

Tarring and feathering might be a good start... I nominate Abbot and DeSatan for the first recipients.
... I think this speaks to the people who are customers of these clowns as well. They pay $90 for the script and who knows how much for the meds of questionable value, if they can get it; rather than pay $0 for the vaccine that is known to work. Is this smart?? This is more than mis-information, this takes a beyond all reason stiff neck in many.
jhu72... to your knowledge, has your Dr. wife ever prescribed any medication off-label?... just curious

If so, I would bet that is a freedom and private transaction between herself and her patients she wouldn't want to lose.

Unfortunately, the IVM/Covid construct has become completely politicized by a concerted effort, (the health establishment and others), to link it to HCQ, anti-vaxxers, and Trump. All lies/misinformation. You know this of course but would never pass up a chance to throw partisan bricks.

At this point, no one stands a chance of acquiring a script of IVM, for either prophylactic or treatment protocols against Covid, in the privacy of their doctor's office. Mission accomplished I guess.
https://www.fda.gov/patients/learn-abou ... rugs-label
... doctors put themselves at risk by prescribing for off-label use. If there is an adverse reaction, or the patient doesn't progress where they would have with some on-label drug, its a lawyers wet dream. Most (not all) off-label use is through approved clinical trials, which if things go well can lead to a label change for the drug.
Well and as I’ve learned from my best Friend who’s managed basically FL and half of Ga for Sanofi and now Regeneron it sounds like between the healthcare system and the increasing consolidation of medical practices into hospital affiliated regional systems that doctors are losing control of the prescription decision making to an administrative class. B

Re: All things CoronaVirus

Posted: Fri Aug 27, 2021 10:09 pm
by jhu72
PizzaSnake wrote: Fri Aug 27, 2021 11:51 am
jhu72 wrote: Fri Aug 27, 2021 9:12 am Americas Frontline Doctors scam.
Fear makes grifting easier. Which circle would Dante assign them to? And which circle for the "mis-informationistas"?

Tarring and feathering might be a good start... I nominate Abbot and DeSatan for the first recipients.
Apparently the meds cost for this group runs from $70 to $700, depending on drug and packaging

Generally through all distribution channels,
... prior to the pandemic, about 3,000 doses of Ivermectin were sold per week
... today, about 88,000 doses per week are sold through those same channels
... Facebook and other social media are awash in Ivermectin sales and advocacy

there is money to be made. there is supposedly a short supply, making it hard to get currently.

Re: All things CoronaVirus

Posted: Fri Aug 27, 2021 10:16 pm
by Typical Lax Dad
jhu72 wrote: Fri Aug 27, 2021 10:09 pm
PizzaSnake wrote: Fri Aug 27, 2021 11:51 am
jhu72 wrote: Fri Aug 27, 2021 9:12 am Americas Frontline Doctors scam.
Fear makes grifting easier. Which circle would Dante assign them to? And which circle for the "mis-informationistas"?

Tarring and feathering might be a good start... I nominate Abbot and DeSatan for the first recipients.
Apparently the meds cost for this group runs from $70 to $700, depending on drug and packaging

Generally through all distribution channels,
... prior to the pandemic, about 3,000 doses of Ivermectin were sold per week
... today, about 88,000 doses per week are sold through those same channels
... Facebook and other social media are awash in Ivermectin sales and advocacy

there is money to be made.
Trust those folks on the internet….not your doctor (unless he/she prescribes Ivermectin & Hydroxychloroquine), not FDA, not WHO, not scientists or pharmaceutical companies…trust the guys on Facebook.