LaxPower Back-Up Stick

jhu72 wrote: ↑Fri Feb 28, 2020 10:00 am

Jim Malone wrote: ↑Fri Feb 28, 2020 9:40 am The vaccine will come out of Israel way sooner than later to the year proposed during presser. - not unless they have had such a drug in testing for a while already - of which I am skeptical. The timeline Fauci gave is pretty aggressive based on my knowledge of the process. To speed it up you would have to take short cuts which compromise saftey and perhaps effectiveness.

And, Corona beer sales taking a hit is the epitome of I don't even know what! - really? I had not heard this.

If it is on every continent, why is it not pandemic? - we clearly already meet the definition. My understanding --> WHO however has not made declaration because of politics. There are legal agreements between countries which are triggered by such a declaration I believe.

Corona is my favorite beer on a hot day. Perhaps this will cause a drop in price.

Ya know i always suspected you'd be a guy who puts fruit in his beer!

6ftstick wrote: ↑Fri Feb 28, 2020 10:06 am

jhu72 wrote: ↑Fri Feb 28, 2020 10:00 am

Jim Malone wrote: ↑Fri Feb 28, 2020 9:40 am The vaccine will come out of Israel way sooner than later to the year proposed during presser. - not unless they have had such a drug in testing for a while already - of which I am skeptical. The timeline Fauci gave is pretty aggressive based on my knowledge of the process. To speed it up you would have to take short cuts which compromise saftey and perhaps effectiveness.

And, Corona beer sales taking a hit is the epitome of I don't even know what! - really? I had not heard this.

If it is on every continent, why is it not pandemic? - we clearly already meet the definition. My understanding --> WHO however has not made declaration because of politics. There are legal agreements between countries which are triggered by such a declaration I believe.

Corona is my favorite beer on a hot day. Perhaps this will cause a drop in price.

Ya know i always suspected you'd be a guy who puts fruit in his beer!

I had to laugh at that one too, 72.
You jumped all over that one, 6ft, well played.

Corona recent launched its line of hard seltzers. Tropical lime, mango, cherry and bat. Good timing.

“We have a public health crisis. Here are the current activities of the WH’s top three officials:
Trump: tweeting about polls
Pence: attending Florida fundraiser
Mulvaney: speaking at CPAC conference
Meanwhile, doctors with relevant knowledge muzzled and market in free fall.”

Michael Bromwich

DMac wrote: ↑Fri Feb 28, 2020 10:31 am I had to laugh at that one too, 72.
You jumped all over that one, 6ft, well played.

Yup... 6ft did good.

a fan wrote: ↑Fri Feb 28, 2020 12:46 am Noooopity-nope-nope.

Not calling Old Salt any of those things. He was simply reporting the story....

And yes, Doc. Hopkins lost that game. Sorry, my man.

Nice recovery on the balance beam. I’m still docking you, like, a gazillion points.

DocBarrister

6ftstick wrote: ↑Fri Feb 28, 2020 9:34 am Ignorant and ridiculously uninformed?

Obviously according to your superior intellect and information the tax payer gets nothing for their investment.

Lets forgo the experienced researchers at the Pharmaceutial companies. You and your brother develop the vaccine.

You're not thinking like a capitalist, and it's clouding your judgement.

If YOU think the taxpayer gets something for these Pharma R&D investments.... why the firetruck would we not simply have a Federal drug research lab, patent anything that works, and license the drugs out to BigPharma and take every single penny of the profits from that research?


Imagine telling your wife "hey lookie here! The Federal Research Lab (tm) had a great year, and our taxes went down again this year as a result! Isn't that great?"


Remember, BigPharma sells globally. So why would you as a taxpayer want to fund their R&D, and then let BigPharma take all the profits????

Your Congressmen, who are on the take from BigPharma, have convinced you this makes sense. Sorry. It doesn't make sense.


Or, of you prefer, give them R&D money for research. And if they strike gold with the R&D, or parts of the R&D? Take an equity position on the patent. If the Drug is profitable? Why wouldn't the taxpayer share in said profits? We put the money up, and took the risk, did we not?



Did you know, for example, that the SBA loan program is actually profitable? They charge enough fees/monies that any failed loans in the program are covered by the fees. THAT is how you run the Federal government profitably.

Make sense?

DMac wrote: ↑Fri Feb 28, 2020 10:31 am I had to laugh at that one too, 72.
You jumped all over that one, 6ft, well played.

That was a great line, 6.

jhu72 wrote: ↑Fri Feb 28, 2020 10:00 am

Jim Malone wrote: ↑Fri Feb 28, 2020 9:40 am The vaccine will come out of Israel way sooner than later to the year proposed during presser. - not unless they have had such a drug in testing for a while already - of which I am skeptical. The timeline Fauci gave is pretty aggressive based on my knowledge of the process. To speed it up you would have to take short cuts which compromise saftey and perhaps effectiveness.

Corona is my favorite beer on a hot day. Perhaps this will cause a drop in price.

From my reading there is already a company that has a vaccine that is heading to FDA for round I clinical trials. I forget the name of the company.

There is an antiviral, remdesivir, a broad based antiviral that has shown promise on MARS and SARS like viruses in both the dish and mice. It has been used on 1 patient with good results but with an N=1 you have no reliability. It is currently in a larger double blind study with results to be done, hopefully, by the first part of April. This would certainly help with containing the outbreak and helping those sick and giving the development of the vaccine more time to ensure efficacy and safety.

No comment on the corona beer thing...................been a Genny Lite guy since, well.....way to early.

jhu72 wrote: ↑Fri Feb 28, 2020 5:57 am WaPo setting the record straight.

The (R)'s criticized Obama for not imposing a travel ban from W African countries experiencing Ebola.

Do you (or anyone else) disagree with Trump's travel ban & how early it was implemented ?

"A Chinese official said some recovered patients had been found to be infectious, suggesting the epidemic may be even harder to eradicate than previously thought.

Lindmeier (WHO) said the WHO was looking very carefully into reports of some people getting re-infected."

WHO press conference

Bart wrote: ↑Fri Feb 28, 2020 12:24 pm

jhu72 wrote: ↑Fri Feb 28, 2020 10:00 am

Jim Malone wrote: ↑Fri Feb 28, 2020 9:40 am The vaccine will come out of Israel way sooner than later to the year proposed during presser. - not unless they have had such a drug in testing for a while already - of which I am skeptical. The timeline Fauci gave is pretty aggressive based on my knowledge of the process. To speed it up you would have to take short cuts which compromise saftey and perhaps effectiveness.

Corona is my favorite beer on a hot day. Perhaps this will cause a drop in price.

From my reading there is already a company that has a vaccine that is heading to FDA for round I clinical trials. I forget the name of the company.

There is an antiviral, remdesivir, a broad based antiviral that has shown promise on MARS and SARS like viruses in both the dish and mice. It has been used on 1 patient with good results but with an N=1 you have no reliability. It is currently in a larger double blind study with results to be done, hopefully, by the first part of April. This would certainly help with containing the outbreak and helping those sick and giving the development of the vaccine more time to ensure efficacy and safety.

No comment on the corona beer thing...................been a Genny Lite guy since, well.....way to early.

This is what I thought Fauci was talking about. He gave no time for R&D, assumed we had something ready to go to trials now, then only 2 phases of clinical trials came up with a minimum of a year (which is quick). Therein lay the problem, people think you invent a drug and it is ready to go out to the public, without clinical testing. The thing to watch out for is Orange Duce trying to subvert this process, which as president he could, allowing the drug to go to production with too little testing. A big big gamble. I actually suspect we will have a battle between NIH / FDA / CDC and Trump as he will get impatient.

Trump is not equipped to handle this emergency. He doesn't know what he doesn't know, is incapable or learning it and that can kill people.

-- only came to Corona late in life. Grew up on natty boh.

old salt wrote: ↑Fri Feb 28, 2020 12:27 pm

jhu72 wrote: ↑Fri Feb 28, 2020 5:57 am WaPo setting the record straight.

The (R)'s criticized Obama for not imposing a travel ban from W African countries experiencing Ebola.

Do you (or anyone else) disagree with Trump's travel ban & how early it was implemented ?

To which travel ban are you referring?

old salt wrote: ↑Fri Feb 28, 2020 12:27 pm

jhu72 wrote: ↑Fri Feb 28, 2020 5:57 am WaPo setting the record straight.

The (R)'s criticized Obama for not imposing a travel ban from W African countries experiencing Ebola.

Do you (or anyone else) disagree with Trump's travel ban & how early it was implemented ?

Obama's policy turned out to be marvelously successful. In retrospect, they handled it very, very well.

Of course, the situations are different, though the argument is much the same.

Travel bans have all sorts of negative effects and it's pretty clear that unless there's a worldwide travel ban from all countries this particular virus will get here.

Far more effective would be ramping up testing protocols of all entrants to the US from any country with suspected virus outbreaks. But we are way, way behind in that regard.

My son and his girlfriend had been out of China for 10 days in Japan, went back to Shanghai just as this was becoming an evident issue, then left for two weeks for scheduled vacation in Thailand, which they then extended. They then flew through Bangkok, to Hong Kong, to Chicago to Ft. Lauderdale. There was a little bit of questioning and at least temperature testing in Bangkok, but none in Hong Kong by the US or arriving in Chicago and clearing customs. Note that while Japan, Shanghai, Thailand, and Hong Kong have not had many cases, it's definitely in those locales to some extent. So, a really good protocol would have been to have tested them so as to be sure. Preferably genetic testing for the virus.

My son did get tagged for increased scrutiny from a terrorist perspective as he'd been in Malaysia (Kuala Lumpur) on business in the past 6 months, but girlfriend not as she hadn't been on that trip. They did get a follow up call on the phone from the CDC, but never were tested.

jhu72 wrote: ↑Fri Feb 28, 2020 12:43 pm

Bart wrote: ↑Fri Feb 28, 2020 12:24 pm

jhu72 wrote: ↑Fri Feb 28, 2020 10:00 am

Jim Malone wrote: ↑Fri Feb 28, 2020 9:40 am The vaccine will come out of Israel way sooner than later to the year proposed during presser. - not unless they have had such a drug in testing for a while already - of which I am skeptical. The timeline Fauci gave is pretty aggressive based on my knowledge of the process. To speed it up you would have to take short cuts which compromise saftey and perhaps effectiveness.

Corona is my favorite beer on a hot day. Perhaps this will cause a drop in price.

From my reading there is already a company that has a vaccine that is heading to FDA for round I clinical trials. I forget the name of the company.

There is an antiviral, remdesivir, a broad based antiviral that has shown promise on MARS and SARS like viruses in both the dish and mice. It has been used on 1 patient with good results but with an N=1 you have no reliability. It is currently in a larger double blind study with results to be done, hopefully, by the first part of April. This would certainly help with containing the outbreak and helping those sick and giving the development of the vaccine more time to ensure efficacy and safety.

No comment on the corona beer thing...................been a Genny Lite guy since, well.....way to early.

This is what I thought Fauci was talking about. He gave no time for R&D, assumed we had something ready to go to trials now, then only 2 phases of clinical trials came up with a minimum of a year (which is quick). Therein lay the problem, people think you invent a drug and it is ready to go out to the public, without clinical testing. The thing to watch out for is Orange Duce trying to subvert this process, which as president he could, allowing the drug to go to production with too little testing. A big big gamble. I actually suspect we will have a battle between NIH / FDA / CDC and Trump as he will get impatient.

Trump is not equipped to handle this emergency. He doesn't know what he doesn't know, is incapable or learning it and that can kill people.

-- only came to Corona late in life. Grew up on natty boh.

My guess, and it is only a guess, is if the stage I goes well it will be pushed through. The drug was developed in hopes of dealing with ebola but it did not pan out. The use in MARS and SARS was an easy jump in logic. What I do not know is if the drug had phase I wen considering it for ebola? I do get the feeling it is a more general antiviral medication so there may be some others out there that may be good candidates?

natty boh was always in the running.................

jhu72 wrote: ↑Fri Feb 28, 2020 12:45 pm

old salt wrote: ↑Fri Feb 28, 2020 12:27 pm

jhu72 wrote: ↑Fri Feb 28, 2020 5:57 am WaPo setting the record straight.

The (R)'s criticized Obama for not imposing a travel ban from W African countries experiencing Ebola.

Do you (or anyone else) disagree with Trump's travel ban & how early it was implemented ?

To which travel ban are you referring?

weak dodge

MDlaxfan76 wrote: ↑Fri Feb 28, 2020 12:46 pm

old salt wrote: ↑Fri Feb 28, 2020 12:27 pm

jhu72 wrote: ↑Fri Feb 28, 2020 5:57 am WaPo setting the record straight.

The (R)'s criticized Obama for not imposing a travel ban from W African countries experiencing Ebola.

Do you (or anyone else) disagree with Trump's travel ban & how early it was implemented ?

Obama's policy turned out to be marvelously successful. In retrospect, they handled it very, very well.

Of course, the situations are different, though the argument is much the same.

Travel bans have all sorts of negative effects and it's pretty clear that unless there's a worldwide travel ban from all countries this particular virus will get here.

Far more effective would be ramping up testing protocols of all entrants to the US from any country with suspected virus outbreaks. But we are way, way behind in that regard.

My son did get ...a follow up call on the phone from the CDC, but never were tested.

It's not realistic to expect that many test kits for a new virus available that quickly or to waste them on travelers without symptoms.

Coronavirus Vaccine 'Weeks' Away From Being Developed, Says Head of Israeli Science Research Institute

https://www.newsweek.com/coronavirus-va ... te-1489694

Bart wrote: ↑Fri Feb 28, 2020 1:26 pm

jhu72 wrote: ↑Fri Feb 28, 2020 12:43 pm

Bart wrote: ↑Fri Feb 28, 2020 12:24 pm

jhu72 wrote: ↑Fri Feb 28, 2020 10:00 am

Jim Malone wrote: ↑Fri Feb 28, 2020 9:40 am The vaccine will come out of Israel way sooner than later to the year proposed during presser. - not unless they have had such a drug in testing for a while already - of which I am skeptical. The timeline Fauci gave is pretty aggressive based on my knowledge of the process. To speed it up you would have to take short cuts which compromise saftey and perhaps effectiveness.

Corona is my favorite beer on a hot day. Perhaps this will cause a drop in price.

From my reading there is already a company that has a vaccine that is heading to FDA for round I clinical trials. I forget the name of the company.

There is an antiviral, remdesivir, a broad based antiviral that has shown promise on MARS and SARS like viruses in both the dish and mice. It has been used on 1 patient with good results but with an N=1 you have no reliability. It is currently in a larger double blind study with results to be done, hopefully, by the first part of April. This would certainly help with containing the outbreak and helping those sick and giving the development of the vaccine more time to ensure efficacy and safety.

No comment on the corona beer thing...................been a Genny Lite guy since, well.....way to early.

This is what I thought Fauci was talking about. He gave no time for R&D, assumed we had something ready to go to trials now, then only 2 phases of clinical trials came up with a minimum of a year (which is quick). Therein lay the problem, people think you invent a drug and it is ready to go out to the public, without clinical testing. The thing to watch out for is Orange Duce trying to subvert this process, which as president he could, allowing the drug to go to production with too little testing. A big big gamble. I actually suspect we will have a battle between NIH / FDA / CDC and Trump as he will get impatient.

Trump is not equipped to handle this emergency. He doesn't know what he doesn't know, is incapable or learning it and that can kill people.

-- only came to Corona late in life. Grew up on natty boh.

My guess, and it is only a guess, is if the stage I goes well it will be pushed through. The drug was developed in hopes of dealing with ebola but it did not pan out. The use in MARS and SARS was an easy jump in logic. What I do not know is if the drug had phase I wen considering it for ebola? I do get the feeling it is a more general antiviral medication so there may be some others out there that may be good candidates?

natty boh was always in the running.................

Certainly possible they could allow it out of the lab after phase 1. That could cut the time in half (maybe a little more). Of course as far as effectiveness is concerned you then have nothing more than a guess. Expectations among the public are then high (Trump would make sure of that) and a failure ruins your reputation (the researchers / drug developer / scientists in general). I want the researchers / clinicians making these decisions and standing behind them - not politicians. A limited release, with well understood caveats, after phase 1 could make sense, a general release much less so I think.