Re: `1
Posted: Wed Jun 28, 2023 4:03 pm
https://www.caclubindia.com/wealth/anth ... _Net_Worthyouthathletics wrote: ↑Wed Jun 28, 2023 9:07 pm cv19 has been very-very good to me, says Fauci: https://twitter.com/isource_news/status ... 73378?s=20
... Red is right. If this guy has real proof, a reputable publisher and venue would be happy to provide him a forum. You will just have to resort to the tired conspiracy theory if you don't believe that.tech37 wrote: ↑Wed Jun 28, 2023 3:52 pmDr. Lawrie: https://www.researchgate.net/profile/Theresa-LawrieRedFromMI wrote: ↑Wed Jun 28, 2023 3:33 pm If they cannot present their data/research/presentations through normal scientific outlets such as peer reviewed journals and science society meetings I have little problem with a characterization of “misinformation,” given that they choose present only through what is considered a misinformation channel.
It’s not like those preferred outlets don’t ever have any kooks…. The American Physical Society has a long standing practice of allowing any paying member to present at a general meeting at least one poster or 12 minute talk. My very first presentation was second to the end of a session on electronic spectra instrumentation, and the room was packed for the next guy who: insisted God gave him the true baryon masses, that he would give anyone $2k is they could _prove_him wrong, and of course he would be the judge. I finished my talk about 2-4 minutes early because it was quite intimidating to face so many in an obscure section…
There's plenty more if you need it. I'm pretty certain she vetted Malhotra's work prior to introducing him at the conference.
Don't you think?
And even if he's wrong, it's not "misinformation" bullsh!t, labeled by captured establishment Drs. and scientists who don't want the boat to be rocked. It's simply information/data that can be challenged and proven as either correct or not. You know, the way science is supposed to work?
So did you read the paper and validate his statistics as you told DMac you would?jhu72 wrote: ↑Tue Jun 27, 2023 1:43 pm... I watched to the end of his talk.DMac wrote: ↑Fri May 05, 2023 8:01 pm Doubt anyone will watch this as it passes the fifteen minute attention span we mostly get in the world today.
If you do, please tell me how you write this guy off as a quack, as one to be ignored. Dumbforkistanians are
very interested in your input here.
"Biased funding research"....like we got from the one gvmt agency who gave us the results of their marijuana research, quite different from what we got when independent researches enter the picture.
https://worldcouncilforhealth.org/multi ... onference/
The first half of his talk was largely a yawn to me. Not new, pharma is a corrupt money making machine. There is a solution, I have advocated for a long time -- take the profit out of it!!! I am called a socialist or worse. There are cases of individual physician corruption, but that is a small number, and relies on big pharma's existence. The part where he claims COVID MRNA does more harm than good, is more interesting. I will need to actually read his paper. He quoted some statistics I am not sure they are valid - looking at the problem the way he did.
A word of caution, he has gone through a change in his perspective, triggered by his father's death. I have seen a couple cases of individuals go through this with friends losing loved ones who have come to blame the medical community, irrationally IMO, not the particular physician involved. The other caution is thinking everyone involved in the COVID vax is involved in a conspiracy. I don't believe that is actually possible.
The jury is out for me.
The earth is flat...............especially up in Canada.tech37 wrote: ↑Thu Jun 29, 2023 7:32 amSo did you read the paper and validate his statistics as you told DMac you would? (BTW, what credentials or expertise do you possess in order to validate anything that Malhotra is presenting?)jhu72 wrote: ↑Tue Jun 27, 2023 1:43 pm... I watched to the end of his talk.DMac wrote: ↑Fri May 05, 2023 8:01 pm Doubt anyone will watch this as it passes the fifteen minute attention span we mostly get in the world today.
If you do, please tell me how you write this guy off as a quack, as one to be ignored. Dumbforkistanians are
very interested in your input here.
"Biased funding research"....like we got from the one gvmt agency who gave us the results of their marijuana research, quite different from what we got when independent researches enter the picture.
https://worldcouncilforhealth.org/multi ... onference/
The first half of his talk was largely a yawn to me. Not new, pharma is a corrupt money making machine. There is a solution, I have advocated for a long time -- take the profit out of it!!! I am called a socialist or worse. There are cases of individual physician corruption, but that is a small number, and relies on big pharma's existence. The part where he claims COVID MRNA does more harm than good, is more interesting. I will need to actually read his paper. He quoted some statistics I am not sure they are valid - looking at the problem the way he did.
A word of caution, he has gone through a change in his perspective, triggered by his father's death. I have seen a couple cases of individuals go through this with friends losing loved ones who have come to blame the medical community, irrationally IMO, not the particular physician involved. The other caution is thinking everyone involved in the COVID vax is involved in a conspiracy. I don't believe that is actually possible.
The jury is out for me.
Or was that "misinformation" claim enough scientific evidence for you not to bother?
Thank you for providing even more evidence that the covid shot does not work.Typical Lax Dad wrote: ↑Mon Jul 03, 2023 6:45 pm https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065129/
Just putting it out there.
Typical Lax Dad wrote: ↑Mon Jul 03, 2023 6:45 pm https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065129/
Just putting it out there.
Will hydro work when washing a load of whites in hot water?
CU88a wrote: ↑Fri Jan 05, 2024 8:06 am DNA in Covid-19 vaccines: 7 pieces of context missed from Florida Surgeon General’s unnecessary warning
KATELYN JETELINA, EDWARD NIRENBERG, AND KRISTEN PANTHAGANI, MD, PHD
JAN 5
Happy 2024!
The first public health rumor of the year came in hot: the Florida Surgeon General sent an email airing his concerns about mRNA Covid-19 vaccines: billions of DNA fragments per dose of Covid-19 mRNA vaccines.
This isn’t the first time he questioned the safety of mRNA Covid-19 vaccines, but it is a new angle. As always, each claim should be evaluated individually based on merit.
Let’s dig in.
First, the kernel of truth.
Rumors typically have a kernel of truth—a core accuracy surrounded by dubious claims. And, in the most complex claims, the molecular biology required to explain in detail why the claims are unfounded spans a few semesters’ worth of material. This makes rumors like these particularly dangerous: it’s hard for the general public to separate hypothetical (and unfounded) concerns from true risks. And it takes a long time to debunk.
What’s the kernel of truth here? There are DNA fragments in Covid-19 vaccines.
But there are seven important pieces of context missing:
1. “Billions of DNA fragments per dose” is relatively small.
Ladapo got this statistic from a recent preprint study with serious methodological problems. But if we assume this number is true, when we look at microscopic levels, there are trillions and trillions of particles in vaccines. For reference, there are about 13 trillion strands of RNA in a Pfizer vaccine alone. “Billions” turns out to be a very small relative quantity.
2. DNA fragments are in ALL vaccines.
Producing vaccines requires us to use cells, and cells contain DNA. This is why DNA fragments are found in all vaccines. DNA fragments aren’t limited to vaccines, either. Insulin, for example, also contains small amounts of DNA from the bacteria used to make it.
Regardless, we try to limit the number because it can impact the immune response. We aim for the purest form of vaccines so they work as intended and consistently. The FDA requires less than 10 ng/dose of residual DNA fragments in any vaccine for full approval.
Multiple regulators across the globe have consistently found vaccines to have acceptable levels of DNA fragments. Even the flawed preprint confirms Covid-19 vaccines’ DNA content is far below any levels indicating a safety or manufacturing concern (see below).
Data for this graph was from this preprint.
3. Cells have safety mechanisms.
Even with small fragments of DNA, humans have a default protection response: when exposed to foreign DNA, whether from food, air, viruses or, yes, vaccines, our bodies destroy it through a shredder (called a DNase)—the DNA gets chopped into tiny fragments and our body recycles them. Our defense mechanisms against foreign DNA are much more extensive than this, but this is a major barrier.
4. It is biologically impossible for random DNA fragments to integrate into our genes.
Even if some DNA fragments are left behind from the shredder, they cannot be inserted into our genes and change our DNA, as Ladapo falsely insinuates. There are two main reasons:
DNA fragments lack opportunity. The vaccines lack the basic tools necessary to alter our genes. (See this previous YLE post.)
DNA fragments lack stability. The DNA is fragmented and, thus, unstable inside the cell. This means it cannot create a dangerous protein.
5. DNA fragments will not impact our children’s genes, either.
Ladapo claims that DNA fragments will impact not just our genes but our children’s genes.
First, if foreign DNA does not affect our genes, it will not affect our children’s genes.
Second, we have two important preclinical studies—studies before human clinical trials—that show the claim is false:
Where does the vaccine go? One study gave a massive dose of vaccine (equivalent to hundreds of times the relevant human dose) to rats and found the vast majority went to lymph nodes, liver, and spleen. About 0.1%—a trivial amount—went into the ovaries and testes. Covid-19 vaccines are not delivering significant doses of foreign DNA to reproductive organs. (And any tiny, tiny, tiny dose that theoretically may get there will quickly meet its demise by the cell’s protection mechanisms.)
Do DNA fragments change genes? Another study evaluated if the vaccine (meaning all parts of the vaccine, including any impurities) impacts the genome through genotoxicity assays. The studies showed no effect.
We would all prefer to have human data, but there’s a great reason why this hasn’t been done in humans: it would require us to surgically take samples from the relevant sites (ovaries and testicles), which would be invasive and unethical.
6. Lipid nanoparticles are safe.
mRNA is very fragile, so it needs to be packaged in fat bubbles (i.e., lipid nanoparticles) to get it to go where it needs to be. Ladapo claims that these lipid nanoparticles make them unsafe.
We’ve seen this rumor throughout the pandemic. But scientists have been working with lipid nanoparticles since the 1960s. There is no evidence that these fat bubbles are dangerous to humans. They get rapidly metabolized and cleared from the body in days.
7. Simian Virus 40 promoter/enhancer (SV40) is also not a concern.
Finally, Ladapo argues that there is a special danger to the mRNA vaccines because the template used to make the mRNA vaccines uses a piece of SV40. This is totally unfounded.
First, some basics. SV40 is a virus first identified in monkey cells, and now its parts are used as a molecular biology tool. The SV40 virus was not used to produce the Covid-19 vaccines; only one part was used (a sequence called a promoter).
For some time, there was concern about the SV40 virus (not the promoter). The whole SV40 virus was once suspected of causing cancer in humans because of some concerning lab studies. In the 1960s, it was discovered SV40 had contaminated some of the polio vaccines because it was present in the cell cultures used to make them. However, we now know even the virus itself is not a concern—studies following polio-vaccinated people for decades found no difference in their risk of cancer compared with those who never received SV40 virus-containing vaccines.
If the virus itself doesn’t cause cancer, there’s no reason to be concerned about small fragments of the promoter.
Bottom line
There are trace quantities of DNA fragments in our mRNA vaccines. But our amazing human immune systems know what to do.
Regardless, we have been tracking the safety of Covid-19 vaccines at unprecedented levels across the globe for more than three years. Scientific evidence from the lab, clinical trials, and epidemiological real-world data continue to verify a highly favorable profile of benefit to risk of Covid-19 vaccines.
Covid-19 vaccines save lives. Unfortunately, many people—including 8,288 Floridians in 2023 alone—continue to lose their lives to Covid-19. Don’t let rumors get in the way of protecting yourself and living a healthy life.
https://open.substack.com/pub/yourlocal ... dium=email
CU88 isn't the one who said that. That was yours truly.tech37 wrote: ↑Fri Jan 05, 2024 9:40 amCU88a wrote: ↑Fri Jan 05, 2024 8:06 am DNA in Covid-19 vaccines: 7 pieces of context missed from Florida Surgeon General’s unnecessary warning
KATELYN JETELINA, EDWARD NIRENBERG, AND KRISTEN PANTHAGANI, MD, PHD
JAN 5
Happy 2024!
The first public health rumor of the year came in hot: the Florida Surgeon General sent an email airing his concerns about mRNA Covid-19 vaccines: billions of DNA fragments per dose of Covid-19 mRNA vaccines.
This isn’t the first time he questioned the safety of mRNA Covid-19 vaccines, but it is a new angle. As always, each claim should be evaluated individually based on merit.
Let’s dig in.
First, the kernel of truth.
Rumors typically have a kernel of truth—a core accuracy surrounded by dubious claims. And, in the most complex claims, the molecular biology required to explain in detail why the claims are unfounded spans a few semesters’ worth of material. This makes rumors like these particularly dangerous: it’s hard for the general public to separate hypothetical (and unfounded) concerns from true risks. And it takes a long time to debunk.
What’s the kernel of truth here? There are DNA fragments in Covid-19 vaccines.
But there are seven important pieces of context missing:
1. “Billions of DNA fragments per dose” is relatively small.
Ladapo got this statistic from a recent preprint study with serious methodological problems. But if we assume this number is true, when we look at microscopic levels, there are trillions and trillions of particles in vaccines. For reference, there are about 13 trillion strands of RNA in a Pfizer vaccine alone. “Billions” turns out to be a very small relative quantity.
2. DNA fragments are in ALL vaccines.
Producing vaccines requires us to use cells, and cells contain DNA. This is why DNA fragments are found in all vaccines. DNA fragments aren’t limited to vaccines, either. Insulin, for example, also contains small amounts of DNA from the bacteria used to make it.
Regardless, we try to limit the number because it can impact the immune response. We aim for the purest form of vaccines so they work as intended and consistently. The FDA requires less than 10 ng/dose of residual DNA fragments in any vaccine for full approval.
Multiple regulators across the globe have consistently found vaccines to have acceptable levels of DNA fragments. Even the flawed preprint confirms Covid-19 vaccines’ DNA content is far below any levels indicating a safety or manufacturing concern (see below).
Data for this graph was from this preprint.
3. Cells have safety mechanisms.
Even with small fragments of DNA, humans have a default protection response: when exposed to foreign DNA, whether from food, air, viruses or, yes, vaccines, our bodies destroy it through a shredder (called a DNase)—the DNA gets chopped into tiny fragments and our body recycles them. Our defense mechanisms against foreign DNA are much more extensive than this, but this is a major barrier.
4. It is biologically impossible for random DNA fragments to integrate into our genes.
Even if some DNA fragments are left behind from the shredder, they cannot be inserted into our genes and change our DNA, as Ladapo falsely insinuates. There are two main reasons:
DNA fragments lack opportunity. The vaccines lack the basic tools necessary to alter our genes. (See this previous YLE post.)
DNA fragments lack stability. The DNA is fragmented and, thus, unstable inside the cell. This means it cannot create a dangerous protein.
5. DNA fragments will not impact our children’s genes, either.
Ladapo claims that DNA fragments will impact not just our genes but our children’s genes.
First, if foreign DNA does not affect our genes, it will not affect our children’s genes.
Second, we have two important preclinical studies—studies before human clinical trials—that show the claim is false:
Where does the vaccine go? One study gave a massive dose of vaccine (equivalent to hundreds of times the relevant human dose) to rats and found the vast majority went to lymph nodes, liver, and spleen. About 0.1%—a trivial amount—went into the ovaries and testes. Covid-19 vaccines are not delivering significant doses of foreign DNA to reproductive organs. (And any tiny, tiny, tiny dose that theoretically may get there will quickly meet its demise by the cell’s protection mechanisms.)
Do DNA fragments change genes? Another study evaluated if the vaccine (meaning all parts of the vaccine, including any impurities) impacts the genome through genotoxicity assays. The studies showed no effect.
We would all prefer to have human data, but there’s a great reason why this hasn’t been done in humans: it would require us to surgically take samples from the relevant sites (ovaries and testicles), which would be invasive and unethical.
6. Lipid nanoparticles are safe.
mRNA is very fragile, so it needs to be packaged in fat bubbles (i.e., lipid nanoparticles) to get it to go where it needs to be. Ladapo claims that these lipid nanoparticles make them unsafe.
We’ve seen this rumor throughout the pandemic. But scientists have been working with lipid nanoparticles since the 1960s. There is no evidence that these fat bubbles are dangerous to humans. They get rapidly metabolized and cleared from the body in days.
7. Simian Virus 40 promoter/enhancer (SV40) is also not a concern.
Finally, Ladapo argues that there is a special danger to the mRNA vaccines because the template used to make the mRNA vaccines uses a piece of SV40. This is totally unfounded.
First, some basics. SV40 is a virus first identified in monkey cells, and now its parts are used as a molecular biology tool. The SV40 virus was not used to produce the Covid-19 vaccines; only one part was used (a sequence called a promoter).
For some time, there was concern about the SV40 virus (not the promoter). The whole SV40 virus was once suspected of causing cancer in humans because of some concerning lab studies. In the 1960s, it was discovered SV40 had contaminated some of the polio vaccines because it was present in the cell cultures used to make them. However, we now know even the virus itself is not a concern—studies following polio-vaccinated people for decades found no difference in their risk of cancer compared with those who never received SV40 virus-containing vaccines.
If the virus itself doesn’t cause cancer, there’s no reason to be concerned about small fragments of the promoter.
Bottom line
There are trace quantities of DNA fragments in our mRNA vaccines. But our amazing human immune systems know what to do.
Regardless, we have been tracking the safety of Covid-19 vaccines at unprecedented levels across the globe for more than three years. Scientific evidence from the lab, clinical trials, and epidemiological real-world data continue to verify a highly favorable profile of benefit to risk of Covid-19 vaccines.
Covid-19 vaccines save lives. Unfortunately, many people—including 8,288 Floridians in 2023 alone—continue to lose their lives to Covid-19. Don’t let rumors get in the way of protecting yourself and living a healthy life.
https://open.substack.com/pub/yourlocal ... dium=emailI'll be... and here I thought Substack (some guy on the internet) wasn't acceptable on fanlax. Guess if it advances the narrative...
Hypocrites.
Ah, I always assumed that was the same person.....using a different account for some reason. My bad.