All things Chinese CoronaVirus

[ggait]

Good news.

Cheap, available, existing drug. Looks like a good rigorous study.

The impact is that it would reduce death rates by around a third among the most severely ill patients admitted to hospital.

So that's positive. But far from a cure-all or vaccine.

[wgdsr]

Dexamethasone seems like a real success. Anyone know more about it? It's the BBCs top story today.

it's a drug that's been used for rheumatoid arthritis and asthma, among others.

here's a trial that was run for over 5 years from 2013 to 2018, published in march, to study its effectiveness in treating acute respiratory distress syndrome (ards). in the trial, seems like it was very successful.
https://www.mdlinx.com/journal-summary/ ... js-7613987
there's a link to the lancet article with more details, hopefully while the lancet was mostly publishing legitimate medical info.

not knowing anything professionally, nor about the details of how this worked in the recovery trial... if the drug could perform similar aid to patients at a certain stage (with ards, managing cytokine storms possibly to allow the immune system to fight the virus without destroying its own organs first), then you could see some success in patients having their bodies have the time and ability to fight off the virus without having to fight itself at the same time.

go back a page and you can see a post of mine regarding the deputy chief investigator and designer of the trial... there's a very good chance he mistakenly had the trial participants take what could have been lethal doses of hcq. i will make another prediction... he/they will face some real consequences if those doses can be found to be fatal. translation: i don't trust the recovery trial folks. at all. surely more data and info will come out after these findings.
however, clinicaltrials.gov has 12 trials listed, none completed, most in recruiting stage:
https://clinicaltrials.gov/ct2/results? ... d=covid+19

so of course look for the WHO, the cdc and the fda to approve its use if they see the good headlines.

[Typical Lax Dad]

Dexamethasone seems like a real success. Anyone know more about it? It's the BBCs top story today.

it's a drug that's been used for rheumatoid arthritis and asthma, among others.

here's a trial that was run for over 5 years from 2013 to 2018, published in march, to study its effectiveness in treating acute respiratory distress syndrome (ards). in the trial, seems like it was very successful.
https://www.mdlinx.com/journal-summary/ ... js-7613987
there's a link to the lancet article with more details, hopefully while the lancet was mostly publishing legitimate medical info.

not knowing anything professionally, nor about the details of how this worked in the recovery trial... if the drug could perform similar aid to patients at a certain stage (with ards, managing cytokine storms possibly to allow the immune system to fight the virus without destroying its own organs first), then you could see some success in patients having their bodies have the time and ability to fight off the virus without having to fight itself at the same time.

go back a page and you can see a post of mine regarding the deputy chief investigator and designer of the trial... there's a very good chance he mistakenly had the trial participants take what could have been lethal doses of hcq. i will make another prediction... he/they will face some real consequences if those doses can be found to be fatal. translation: i don't trust the recovery trial folks. at all. surely more data and info will come out after these findings.
however, clinicaltrials.gov has 12 trials listed, none completed, most in recruiting stage:
https://clinicaltrials.gov/ct2/results? ... d=covid+19

so of course look for the WHO, the cdc and the fda to approve its use if they see the good headlines.

This is very good news. Like I said, I don’t know why Hydroxychloroquine and Redemisvir got all of the attention. Let the professionals carry the water.

[CU77]

Meanwhile, back at the ranch...

Gov. Doug Ducey fires the scientists who warn he's making a mistake by reopening Arizona
Just hours after Gov. Ducey announced on Monday that he’s accelerating the reopening of parts of the state’s economy, state health officials told a team of university experts to stop working on models that project what will happen next.

https://www.azcentral.com/story/opinion ... 175510002/

So behind the curve. In Florida, DeSantis fired his top data scientist a month ago:

https://www.npr.org/sections/coronaviru ... -scientist

And how's that working out?

Days after Florida Gov. Ron DeSantis (R) waved off concerns about a growing coronavirus outbreak, the state Tuesday tallied its highest single-day count of new cases at 2,783, according to data tracked by The Washington Post.

Totals for Florida’s seven-day average of new cases have hit record highs for the past nine days; a week ago, the state’s one-day total of new cases was 1,096. The average of hospitalizations is up as well, and Florida is reporting a U.S.-high 55 deaths on Tuesday, up from seven on Monday.

The state’s infection totals have steadily grown since the start of June, roughly two weeks after its “full phase-one” reopening plan began.

https://www.washingtonpost.com/nation/2 ... update-us/

[ardilla secreta]

Fun times in Tucson. It’s 104F, there’s a raging mountain fire that’s forcing evacuations and the mayor is begging the governor to allow mandatory mask wearing in their city which is merely a recommendation statewide. Oh and coronavirus for all.

[CU77]

And more fun times in the Sunshine State:

After months of social distancing and staying home, Erika Crisp was excited to go out with 15 of her friends to a newly reopened bar in Jacksonville, Florida. But she now regrets the decision after all 16 of them tested positive for the new coronavirus, COVID-19 — along with seven of the bar’s employees.
…
Crisp said that she and her friends should have been more cautious.

“I think we were careless, and we went out into a public place when we should not have. And we were not wearing masks. I think we had a whole 'out of sight, out of mind' mentality,” she said. “The state opens back up and said everybody was fine, so we took advantage of that.”

Crisp said she learned from this experience, and that the state should not have reopened.

“We should be wearing masks. We should be social distancing,” she said. “It was too soon to open everything back up.”

https://people.com/health/health-care-w ... orida-bar/

[ardilla secreta]

I just don’t get why people aren’t wearing masks and government leaders making it easier by mandating it. The coronavirus isn’t going away for some time, we should be taking measures to reduce the spread. Some Americans treat coronavirus like a diet. Work hard at it for a couple months then give up. I’m glad I live in New York State where mask wearing is mandatory by law.

[Brooklyn]

tRUMP to hold a rally in Oklahoma where people will be spreading viruses:


Supporters form line ahead of Trump rally in Tulsa

https://www.kjrh.com/news/local-news/su ... y-in-tulsa

https://www.theguardian.com/us-news/202 ... ncellation

Trump claims 1m want tickets for Tulsa rally opposed by top health official
Newspaper raises concern over public health and race relations as president plans event in venue holding 19,000


tRUMP claims one million people want tickets!



The US president’s return to the campaign trail is part of Trump’s attempt to reopen an economy battered by a pandemic which has killed more than 115,000 Americans. Over the weekend, cases were reported to be rising in Oklahoma and other mostly Republican-led states which have been reopening since late May.



How many will die and cause others to die?

[jhu72]

Meanwhile in other news: HCQ and CQ have been removed from the FDA list for Emergency Use (compassionate care exemption). We have 66 million doses in the national emergency stockpile. This is what happens when you let politicians, know nothing would be dictators and television scam artists (Fox News) override the science. Maybe now lupus and other autoimmune disease patients where it has proven effective can get their prescriptions filled.

[holmes435]

In just 24 hours, Brazil sets a grim new record with almost 35,000 new coronavirus cases

"The country, which has the second-highest number of coronavirus cases and deaths in the world, after the United States, reported 34,918 new cases and 1,282 new deaths in the past 24 hours."

Sad stuff

[jhu72]

In just 24 hours, Brazil sets a grim new record with almost 35,000 new coronavirus cases

"The country, which has the second-highest number of coronavirus cases and deaths in the world, after the United States, reported 34,918 new cases and 1,282 new deaths in the past 24 hours."

Sad stuff

… another know nothing dictator

[6ftstick]

In just 24 hours, Brazil sets a grim new record with almost 35,000 new coronavirus cases

"The country, which has the second-highest number of coronavirus cases and deaths in the world, after the United States, reported 34,918 new cases and 1,282 new deaths in the past 24 hours."

Sad stuff

… another know nothing dictator

riddle me this smart rump

Why after 4 months of extreme measures to flatten the curve is Dr Faucci saying the new cases across the south and southwest are first wave related.

First wave. So nothing that could have been done since this virus flared can stop it from running its course.

[CU88]

Facts on the current COVID situation here in the USA

The graphics on the link are telling
https://threadreaderapp.com/thread/1273 ... 09408.html


April 27 was the last time there was a White House coronavirus task force briefing, leaving us with more than a month without regular updates from the group Vice President Mike Pence was tapped to lead. (1/24)

Today, Vice President Pence wrote an op-ed in the @WSJ touting America’s success in fighting the coronavirus writing, “...we are winning the fight against the invisible enemy.” Let’s break down some of his claims this week. (2/24)

Opinion | There Isn’t a Coronavirus ‘Second Wave’
With testing, treatments and vaccine trials ramping up, we are far better off than the media report.
https://on.wsj.com/3ear4r8

PENCE: “While talk of an increase in cases dominates cable news coverage, more than half of states are actually seeing cases decline or remain stable.” (3/24)

Yes, compared to last week, 22 states are seeing a decline in daily cases, 10 are stable, but 18 states have an increase of cases. (4/24)

That’s significant because we have states reopening while cases are still on the rise. Remember, the original White House guidelines said states should have a “downward trajectory” of cases or a declining share of positive tests for a 14-day span before gradually opening. (5/24)

PENCE: “Some of the increase in cases you're seeing in states is a reflection of a dramatic increase in testing." (6/24)

That’s not how this works. This may seem counter intuitive, but if you are doing enough testing, cases should start to go down because you are finding people early before they spread it. Let’s look at a few state examples: (7/24)

New York - testing is clearly up and cases are down (8/24)

Florida - testing is roughly holding steady and yet cases are climbing. (9/24)

Oklahoma - cases are going up while testing has actually been going down (10/24)

Vice President Pence also has touted testing success, saying, “As of this week, we are performing roughly 500,000 tests a day, and more than 23 million tests have been performed in total.” (11/24)

This is true, according to data from the Covid Tracking Project. But that doesn’t mean it’s enough. Researchers at Harvard said we would need 5 mil tests per DAY by early June and 20 mil tests per day by late July to safely reopen (12/24)

PENCE: “In recent days, the media has taken to sounding the alarm bells over a “second wave” of coronavirus infections. Such panic is overblown.” (13/24)

The truth is - we are still in the thick of the first wave, technically, so we cannot even begin talking about what a second wave might look like. Take a look. (14/24)

Compare that to what it looked like when Italy saw its new cases dramatically drop off. That’s more of what you want to see to declare the first peak or wave is close to ending. We aren’t there yet. (15/24)

PENCE: “[President Trump] rallied the American people to embrace social-distancing guidelines.” However, we have seen President Trump continue to publicly demonstrate that he does not wear a mask around others. (16/24)

At today’s signing of an executive order for police reform, White House officials were seen standing closely together and talking without masks - including President Trump (17/24)

A recent study published in The Lancet emphasized the importance of masks - There’s a 17.4% chance of transmission if you don’t wear a mask or N95, but only a 3.1% chance if you wear a mask. (18/24)

Social distancing and masks reduce risk of getting Covid-19, review finds
Physical distancing, face masks and eye protection prevent spread of Covid-19, a review finds. So does handwashing.
And we know that President Trump is planning to hold an indoor rally in Tulsa, Oklahoma where the venue can hold around 20,000 people. He also plans to utilize the convention hall next door that can hold an additional 40,000 people. (19/24)

CDC guidelines for events or gatherings would classify this rally as a high risk event considering it’s indoors, there will be attendees from outside the local area and it’ll be difficult to practice social distancing. (20/24)

PENCE: “In a very real sense they’ve flattened the curve. The number of cases in Oklahoma has declined precipitously." (21/24)

Contrary to the Vice President’s claims, the state's infection curve has been rising in recent days. The director of the Tulsa Health Department said he wished the campaign rally would be postponed. (22/24)

While we have flattened the curve in some places, the fight is far from over. And the way to win is not by declaring a premature victory. Yes, scientists all over the world are working to find a vaccine, but we still have to buy them time to do their job. (23/24)

We know that the basics - wearing a mask, staying at home, social distancing and washing our hands - work. But we also need testing, contact tracing and government leadership to make sure we can all beat this thing together. (24/24)

[6ftstick]

Meanwhile in other news: HCQ and CQ have been removed from the FDA list for Emergency Use (compassionate care exemption). We have 66 million doses in the national emergency stockpile. This is what happens when you let politicians, know nothing would be dictators and television scam artists (Fox News) override the science. Maybe now lupus and other autoimmune disease patients where it has proven effective can get their prescriptions filled.

Wish we had a media that could tell us the truth. Because there are ample numbers of drs on the other side of this decision.

Check this Drs credentials—he's an hydroxychloroquine PROPONENT

Dr. Stephen Marshall Smith M.D. (born 1963) is an American physician specializing in Infectious Disease with primary focus in virology. He is from the small northern New Jersey town of Essex Fells. He graduated in 1985 Magna Cum Laude from Duke University. He then later graduated top of his class at Yale School of Medicine in 1989. He performed his internal residency in 2 years at the University of Virginia, doing a half year at St. Michael’s Medical Center in Newark, New Jersey. Currently, Dr. Smith operates out of St. Barnabas Hospital in Livingston, NJ.

He then began a fellowship in infectious diseases at National Institute of Allergy and Infectious Disease in Bethesda, MD under renowned physicians such as Dr. Anthony Fauci.

Dr. Smith was a leading researcher in HIV AIDS for a number of years, trained under renowned Dr. David Ho, discovered new HIV-2 viruses groups, and holds two patents in research and drugs related to the disease.

The Smith Center for Infectious Diseases and Urban Health was developed to address infectious diseases in the inner city.

EDUCATION:
1985 A.B. – Duke University
1989 M.D. – Yale University School of Medicine

POSTDOCTORAL TRAINING:
1989-1991: Internal Medicine Residency, University of Virginia, Charlottesville, VA
1992 (Jan.-Jun.): Internal Medicine Residency, St. Michael’s Medical Center, Newark, NJ
1992-1995 Medical Staff Fellow in Infectious Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD
1995-1996 Post-Doc, Molecular Virology Section, Laboratory of Molecular Microbiology, National Institutes of Allergy and Infectious Diseases, Bethesda, MD
1996-1998 Research Scientist, Laboratory of Animal Models of AIDS, Aaron Diamond AIDS Research Center, Tuxedo and Manhattan, NY

LICENSURE: New Jersey Medical License

CERTIFICATIONS:
1986 Part I of the National Board of Medical Examiners
1989 Part II of the National Board of Medical Examiners
1990 Part III of the National Board of Medical Examiners
1992 Board Certification Internal Medicine – 145346
1994 Board Certification Infectious Diseases – 145346
2004 Board Recertification Infectious Diseases – 145346

[RedFromMI]

In just 24 hours, Brazil sets a grim new record with almost 35,000 new coronavirus cases

"The country, which has the second-highest number of coronavirus cases and deaths in the world, after the United States, reported 34,918 new cases and 1,282 new deaths in the past 24 hours."

Sad stuff

… another know nothing dictator

riddle me this smart rump

Why after 4 months of extreme measures to flatten the curve is Dr Faucci saying the new cases across the south and southwest are first wave related.

First wave. So nothing that could have been done since this virus flared can stop it from running its course.

Plenty could have been done. Since these other states are seeing cases now it generally is because when reopening there has been too little social distancing. Requiring mask wearing when indoors in public/stores/restaurants. Some areas still need more testing - Oklahoma's testing numbers are going down even while cases (and positive tests) are going up. But now it seems that the SD measures that work (keep 6 feet apart, minimize time indoors outside of your own home, wear masks in public) are not being used to the level they should.

And as far as your doctor Smith - he picked what ended up on the wrong side... No real data so far really supports HCQ, and in fact there IS data that says it can hurt (make other treatments less effective, side effect issues). Is he still plugging it? Then he is not helping. Science will move on to better things and leave him behind.

[jhu72]

In just 24 hours, Brazil sets a grim new record with almost 35,000 new coronavirus cases

"The country, which has the second-highest number of coronavirus cases and deaths in the world, after the United States, reported 34,918 new cases and 1,282 new deaths in the past 24 hours."

Sad stuff

… another know nothing dictator

riddle me this smart rump

Why after 4 months of extreme measures to flatten the curve is Dr Faucci saying the new cases across the south and southwest are first wave related.

First wave. So nothing that could have been done since this virus flared can stop it from running its course.

… right, nothing can be done. You don't thinks so, the curves prove you wrong! The social distancing has been effective when instituted and recommendations followed. The problems have occurred when the know nothings like you urge the circumvention of the recommendations. 120K dead and it could have been much worse. The only people who think this is over are the know nothings trying to rush openings. The curves which have been good news the past 3 - 4 weeks will not look as good a month from now (in the US).

[6ftstick]

In just 24 hours, Brazil sets a grim new record with almost 35,000 new coronavirus cases

"The country, which has the second-highest number of coronavirus cases and deaths in the world, after the United States, reported 34,918 new cases and 1,282 new deaths in the past 24 hours."

Sad stuff

… another know nothing dictator

riddle me this smart rump

Why after 4 months of extreme measures to flatten the curve is Dr Faucci saying the new cases across the south and southwest are first wave related.

First wave. So nothing that could have been done since this virus flared can stop it from running its course.

Plenty could have been done. Since these other states are seeing cases now it generally is because when reopening there has been too little social distancing. Requiring mask wearing when indoors in public/stores/restaurants. Some areas still need more testing - Oklahoma's testing numbers are going down even while cases (and positive tests) are going up. But now it seems that the SD measures that work (keep 6 feet apart, minimize time indoors outside of your own home, wear masks in public) are not being used to the level they should.

And as far as your doctor Smith - he picked what ended up on the wrong side... No real data so far really supports HCQ, and in fact there IS data that says it can hurt (make other treatments less effective, side effect issues). Is he still plugging it? Then he is not helping. Science will move on to better things and leave him behind.

Excuse me. BUT Dr Faucci says this is FIRST WAVE. Not caused by REOPENING.

My doctor smith? So in your TDS you can't accept that hes a skilled intelligent physician.Hes been gettin positive results with the hydroxy combo since april.

The ease at which you dismiss him and others like him enhances the belief that this aversion to hydroxy is purely Trump driven.

Thats why I prefaced the post by wishing we had a media would could trust.

[6ftstick]

In just 24 hours, Brazil sets a grim new record with almost 35,000 new coronavirus cases

"The country, which has the second-highest number of coronavirus cases and deaths in the world, after the United States, reported 34,918 new cases and 1,282 new deaths in the past 24 hours."

Sad stuff

… another know nothing dictator

riddle me this smart rump

Why after 4 months of extreme measures to flatten the curve is Dr Faucci saying the new cases across the south and southwest are first wave related.

First wave. So nothing that could have been done since this virus flared can stop it from running its course.

… right, nothing can be done. You don't thinks so, the curves prove you wrong! The social distancing has been effective when instituted and recommendations followed. The problems have occurred when the know nothings like you urge the circumvention of the recommendations. 120K dead and it could have been much worse. The only people who think this is over are the know nothings trying to rush openings. The curves which have been good news the past 3 - 4 weeks will not look as good a month from now (in the US).

And yet you cheer for 10's of thousands of protestors week after week packed tightly out in the streets all across america

Your TDS is showing.

[RedFromMI]

In just 24 hours, Brazil sets a grim new record with almost 35,000 new coronavirus cases

"The country, which has the second-highest number of coronavirus cases and deaths in the world, after the United States, reported 34,918 new cases and 1,282 new deaths in the past 24 hours."

Sad stuff

… another know nothing dictator

riddle me this smart rump

Why after 4 months of extreme measures to flatten the curve is Dr Faucci saying the new cases across the south and southwest are first wave related.

First wave. So nothing that could have been done since this virus flared can stop it from running its course.

Plenty could have been done. Since these other states are seeing cases now it generally is because when reopening there has been too little social distancing. Requiring mask wearing when indoors in public/stores/restaurants. Some areas still need more testing - Oklahoma's testing numbers are going down even while cases (and positive tests) are going up. But now it seems that the SD measures that work (keep 6 feet apart, minimize time indoors outside of your own home, wear masks in public) are not being used to the level they should.

And as far as your doctor Smith - he picked what ended up on the wrong side... No real data so far really supports HCQ, and in fact there IS data that says it can hurt (make other treatments less effective, side effect issues). Is he still plugging it? Then he is not helping. Science will move on to better things and leave him behind.

Excuse me. BUT Dr Faucci says this is FIRST WAVE. Not caused by REOPENING.

My doctor smith? So in your TDS you can't accept that hes a skilled intelligent physician.Hes been gettin positive results with the hydroxy combo since april.

The ease at which you dismiss him and others like him enhances the belief that this aversion to hydroxy is purely Trump driven.

Thats why I prefaced the post by wishing we had a media would could trust.

I don't care what Fauci says about first/second wave. Some states (actually many) are reopening without meeting the criteria for doing so. So they never really got over the first wave, but the reopening is what is causing the increases.

And for Dr. Smith - I will trust double blind test numbers over any single physician - no matter what his/her credentials are. And since he has been one of the ones showing up on Fox (especially Ingraham) plugging I would say that his politics are getting confused for his science or lack of.

Where is his double blind study?

[jhu72]

In just 24 hours, Brazil sets a grim new record with almost 35,000 new coronavirus cases

"The country, which has the second-highest number of coronavirus cases and deaths in the world, after the United States, reported 34,918 new cases and 1,282 new deaths in the past 24 hours."

Sad stuff

… another know nothing dictator

riddle me this smart rump

Why after 4 months of extreme measures to flatten the curve is Dr Faucci saying the new cases across the south and southwest are first wave related.

First wave. So nothing that could have been done since this virus flared can stop it from running its course.

Plenty could have been done. Since these other states are seeing cases now it generally is because when reopening there has been too little social distancing. Requiring mask wearing when indoors in public/stores/restaurants. Some areas still need more testing - Oklahoma's testing numbers are going down even while cases (and positive tests) are going up. But now it seems that the SD measures that work (keep 6 feet apart, minimize time indoors outside of your own home, wear masks in public) are not being used to the level they should.

And as far as your doctor Smith - he picked what ended up on the wrong side... No real data so far really supports HCQ, and in fact there IS data that says it can hurt (make other treatments less effective, side effect issues). Is he still plugging it? Then he is not helping. Science will move on to better things and leave him behind.

The HCQ / CQ story was preordained. These are old drugs (50 years) that have been well studied. Same thing every time they are properly studied. Little to no positive effect on the disease, significant side effects - always the same. COVID-19 is at least the 10th rodeo for these drugs. There are always true believers (invested individuals on the science side) and camp followers for specific drugs. Of course the know nothings don't understand this and are easily sucked in by the con artists.