In the D2 Women’s National Championship Tournament, these are today’s Best Games in order:
| – | Team | Rank | VS | Rank | Opp Team | Details |
| 1 | Grand Valley State | #6 | vs | #3 | Regis (CO) | 05/13/2022 |
| 2 | Queens | #1 | vs | #10 | Tampa | 05/13/2022 |
| 3 | Florida Southern | #8 | vs | #5 | Wingate | 05/13/2022 |
| 4 | UIndy | #7 | vs | #12 | Lindenwood | 05/13/2022 |
| 5 | East Stroudsburg | #2 | vs | #19 | Mercyhurst | 05/13/2022 |
| 6 | Stonehill | #17 | vs | #9 | Mercy | 05/13/2022 |
| 7 | Adelphi | #11 | vs | #18 | Le Moyne | 05/13/2022 |
| 8 | West Chester | #4 | vs | #27 | Seton Hill | 05/13/2022 |
