Today’s Best Games (in order)
| – | Team | Rank | VS | Rank | Opp Team | Details |
| 1 | Tufts | #9 | vs | #6 | Bowdoin | 4/27/2022 |
| 2 | York | #8 | vs | #16 | Stevenson | 4/27/2022 |
| 3 | Catholic | #29 | vs | #4 | Salisbury | 4/27/2022 |
| 4 | Middlebury | #20 | vs | #13 | Williams | 4/27/2022 |
| 5 | Wesleyan | #22 | vs | #33 | Connecticut College | 4/27/2022 |
| 6 | Amherst | #14 | vs | #43 | Trinity | 4/27/2022 |
| 7 | Cabrini | #21 | vs | #45 | Scranton | 4/27/2022 |
| 8 | Lynchburg | #11 | vs | #65 | Bridgewater | 4/27/2022 |
| 9 | Baldwin Wallace | #42 | vs | #58 | Ohio Northern | 4/27/2022 |
| 10 | Shenandoah | #83 | vs | #19 | Washington and Lee | 4/27/2022 |
| 11 | Arcadia | #67 | vs | #40 | Stevens | 4/27/2022 |
| 12 | Brockport | #70 | vs | #46 | Geneseo | 4/27/2022 |
| 13 | Oswego | #88 | vs | #30 | Cortland | 4/27/2022 |
| 14 | Misericordia | #71 | vs | #76 | DeSales | 4/27/2022 |
| 15 | John Carroll | #28 | vs | #121 | Mount Union | 4/27/2022 |
| 16 | Elmhurst | #78 | vs | #81 | Carthage | 4/27/2022 |
| 17 | Colby | #55 | vs | #110 | Bates | 4/27/2022 |
| 18 | Montclair State | #75 | vs | #94 | Kean | 4/27/2022 |
| 19 | Western New England | #44 | vs | #126 | Roger Williams | 4/27/2022 |
| 20 | Guilford | #146 | vs | #38 | Hampden-Sydney | 4/27/2022 |
| 21 | Wentworth | #131 | vs | #60 | Endicott | 4/27/2022 |
| 22 | Lebanon Valley | #118 | vs | #104 | Widener | 4/27/2022 |
| 23 | Lasell | #140 | vs | #85 | Norwich | 4/27/2022 |
| 24 | Grove City | #37 | vs | #194 | Washington and Jefferson | 4/27/2022 |
| 25 | Randolph-Macon | #36 | vs | #196 | Ferrum | 4/27/2022 |
