These are next weekend’s Quarterfinal Games in order of Best Games:
| – | Team | Rank | VS | Rank | Opp Team | Details |
| 1 | Notre Dame | #3 | vs | #5 | Maryland | 05/23/2021 |
| 2 | Duke | #1 | vs | #9 | Loyola | 05/23/2021 |
| 3 | Georgetown | #6 | vs | #4 | Virginia | 05/22/2021 |
| 4 | North Carolina | #2 | vs | #13 | Rutgers | 05/22/2021 |
