These are Today’s Best Games:
| – | Team | Rank | VS | Rank | Opp Team | Details |
| 1 | Syracuse | #2 | vs | #10 | Loyola | 05/16/2021 |
| 2 | Notre Dame | #5 | vs | #9 | Virginia | 05/16/2021 |
| 3 | North Carolina | #1 | vs | #15 | James Madison | 05/16/2021 |
| 4 | Boston College | #3 | vs | #14 | Temple | 05/16/2021 |
| 5 | Northwestern | #4 | vs | #13 | Denver | 05/16/2021 |
| 6 | Florida | #8 | vs | #11 | Jacksonville | 05/16/2021 |
| 7 | Stony Brook | #7 | vs | #16 | Rutgers | 05/16/2021 |
| 8 | Duke | #6 | vs | #17 | Maryland | 05/16/2021 |
