| – | Team | Rank | VS | Rank | Opp Team | Details |
| 1 | Auburn (AL) | #1 | vs | #2 | Hoover (AL) | 04/11/2021 |
| 2 | Auburn (AL) | #1 | vs | #9 | Homewood (AL) | 04/10/2021 |
| 3 | Huntsville (AL) | #6 | vs | #5 | Mountain Brook (AL) | 04/10/2021 |
| 4 | Helena (AL) | #14 | vs | #3 | Vestavia (AL) | 04/10/2021 |
| 5 | Oak Mountain (AL) | #4 | vs | #13 | Bob Jones (AL) | 04/10/2021 |
| 6 | Oak Mountain (AL) | #4 | vs | #14 | Helena (AL) | 04/11/2021 |
| 7 | John Carroll (AL) | #7 | vs | #12 | Thompson (AL) | 04/09/2021 |
| 8 | Thompson (AL) | #12 | vs | #10 | Spain Park (AL) | 04/11/2021 |
