This weekend, there are numerous games and several are quality games. These games, in order, are:
| – | Team | VS | Opp Team | Details |
| 1 | UIndy | vs | Notre Dame (OH) | 3/13/2021 |
| 2 | Limestone | vs | Lincoln Memorial | 3/13/2021 |
| 3 | Belmont Abbey | vs | Lees-McRae | 3/13/2021 |
| 4 | Rockhurst | vs | McKendree | 3/14/2021 |
| 5 | North Greenville | vs | Mount Olive | 3/13/2021 |
| 6 | Lenoir-Rhyne | vs | Tusculum | 3/13/2021 |
| 7 | Mars Hill | vs | Queens | 3/13/2021 |
| 8 | Charleston (WV) | vs | Barton | 3/13/2021 |
| 9 | Lee | vs | Lewis | 3/14/2021 |
| 10 | Lewis | vs | Alabama-Huntsville | 3/13/2021 |
| 11 | Lander | vs | Lee | 3/13/2021 |
| 12 | Wingate | vs | Coker | 3/13/2021 |
| 13 | Newberry | vs | Catawba | 3/14/2021 |
| 14 | Chowan | vs | Converse | 3/13/2021 |
| 15 | Erskine | vs | Southern Wesleyan | 3/13/2021 |
| 16 | Ursuline | vs | Ashland | 3/13/2021 |
