| Day | Road Team | Home Team |
| Saturday | Merrimack | Boston University |
| Saturday | Sankofa Lacrosse Alliance | Hampton |
| Saturday | Navy | Jacksonville (@UNC) |
| Saturday | Vermont | Maryland |
| Saturday | Jacksonville | North Carolina |
| Saturday | Navy | North Carolina |
| Saturday | Marquette | Ohio State |
| Saturday | Providence | Utah |
| Sunday | Molloy (D2) | NJIT |
| Sunday | Detroit Mercy | Notre Dame |
| Sunday | Bucknell | Virginia |
