Biggest Games is defined as the games with the most Game Points. i.e. When you add together the Points of the two relevant teams, that is the Game Points.
Two points that are worthy of mention is that this list changes after most every game and the top teams accumulate more Points as the season progresses. In other words, these are the biggest games right now but as the season progresses, many of these will be replaced. For example, the Championship Final will all but certainly be the #1.
| – | Pts | B Games | – | – |
| 1 | 2,836 | Penn State | Yale | 2/23 |
| 2 | 2,798 | Ohio State | Penn State | 4/7 |
| 3 | 2,798 | Maryland | Penn State | 3/31 |
| 4 | 2,768 | Maryland | Ohio State | 4/20 |
| 5 | 2,641 | Penn | Yale | 3/30 |
| 6 | 2,634 | Penn | Penn State | 3/2 |
| 7 | 2,604 | Maryland | Penn | 2/16 |
| 8 | 2,600 | Loyola | Virginia | 2/9 |
| 9 | 2,599 | Cornell | Yale | 3/16 |
| 10 | 2,592 | Cornell | Penn State | 3/8 |
| 11 | 2,550 | Notre Dame | Ohio State | 3/23 |
| 12 | 2,550 | Maryland | Notre Dame | 3/3 |
| 13 | 2,541 | Duke | Loyola | 3/8 |
| 14 | 2,522 | Duke | Virginia | 4/13 |
| 15 | 2,515 | Syracuse | Virginia | 3/2 |
| 16 | 2,456 | Notre Dame | Virginia | 3/16 |
| 17 | 2,456 | Duke | Syracuse | 3/24 |
| 18 | 2,452 | Villanova | Yale | 2/16 |
| 19 | 2,451 | Duke | Penn | 2/23 |
| 20 | 2,446 | Penn State | Villanova | 2/2 |
